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Abstract                 Volume:3  Issue-5  Year-2016          Original Research Articles

IJCRBP is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCRBP Articles.

Online ISSN : 2349-8080
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Preparation and Characterization of Some New Schiff Bases Compounds with the Study of Biological Effectiveness
Natiq G. Ahmed and Hussein Y. Al-Hashimi*
Department of Chemistry, College of Education for Pure Science, University of Mosul, Mosul, Iraq
*Corresponding author

style="text-align: justify;">A new series of Schiff bases compounds that contains a set of one or more azomethine groups through the reactance compounds (3-Morpholino-1-(3-nitrophenyl)-3-(4-nitrophenyl) propan-1-one, Terephthalaldehyde, Benzylidene acetophenone) with different aromatic amines (2-Aminobenzothiazole, 4-Bromo-2-methylaniline, 5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-amine, 4-amino-N-(5-methyl isoxazol-3-yl) benzenesulfonamide, 2-Aminoanthracene-9,10-dione, 4-(phenyldiazenyl) aniline, 5-(2-chlorophenyl)-1,3,4-thiadiazol-2-amine, Melamine, P-Phenylenediamine) using glacial acetic acid as a catalyst agent (1-10). The synthesized compounds were identified using physical and spectral methods (melting points, colour change, Thin Layer Chromatography, infrared spectra, ultraviolet spectra and nuclear magnetic resonance spectra) and biological effectiveness has also been measured for some of the prepared compounds against the growth of bacteria, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Compounds [1, 4, 7, 8 and 10] showed moderate antibacterial activity (inhibition zone 11-20 mm) on Staphylococcus aureus.

Keywords: Antibacterial activity, Chalcone derivatives, Schiff bases
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How to cite this article:

Ahmed, N. G., Al-Hashimi, H. Y., 2016. Preparation and characterization of some new Schiff bases compounds with the study of biological effectivenessInt.J.Curr.Res.Biosci.Plantbiol. 3(5): 127-136. doi: http://dx.doi.org/10.20546/ijcrbp.2016.305.020
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