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Abstract                 Volume:3  Issue-5  Year-2016          Original Research Articles

IJCRBP is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCRBP Articles.

Online ISSN : 2349-8080
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Effect of 1,4-Dioxane with or without Vitamin C on Rabbits' Blood and Histology
A. M. Abdelhamid1*, W. A. Khalil1, A. A. M. Abdel Hamid2, Rehab F. S. A. Ismail1and Manar A. Almnsy1
1Department of Animal Production, Faculty of Agriculture, Al-Mansoura University, Egypt 2Department of Histology and Cell Biology, Faculty of Medicine, Al-Mansoura University, Egypt
*Corresponding author

A feeding trial for 60 days was carried out on rabbits to study the effects of 1,4-dioxane (3.2mg/Kg) including diets with or without vitamin C (1g/Kg diet, as antioxidant) on their blood profile and some internal organs' histology (kidney, liver and testis). From the obtained blood results and histological examination, it could be concluded that the dietary inclusion of 1,4-dioxane was responsible for occurring a case of multiple anemia [aplastic (toxic), leukemia toxicity, and malnutrition] besides toxic hepatic and biliary tract disease, dehydration, steatorrhea, edema, myocardial infarction and/or excessive protein catabolism.

Keywords: Biochemistry,Dioxane,Hematology,Histology,Rabbits
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How to cite this article:

Abdelhamid, A. M., Khalil, W. A., Abdel Hamid, A. A. M., Ismail, R. F. S. A., Almnsy, M. A., 2016. Effect of 1,4-dioxane with or without vitamin C on rabbits' blood and histology. Int.J.Curr.Res.Biosci.Plantbiol. 3(5): 113-119 . doi: http://dx.doi.org/10.20546/ijcrbp.2016.305.018
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