Abstract                 Volume:6  Issue-4  Year-2019          Original Research Articles

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A review of chemical constituents and pharmacological properties of Hibiscus sabdariffa L.
Abiodun Olusoji Owoade*, Adewale Adetutu and Olubukola Sinbad Olorunnisola
Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomosho, Nigeria
*Corresponding author
Abstract:

Hibiscus sabdariffa is a medicinal plant that is consumed for its health benefits, juice/concoction prepared from the plant is taken as a preventive/curative measures against diabetes and hypertension. The antihypertensive and other pharmacological properties such as antibacterial, anti-oxidant, nephro- and hepato-protective, renal/diuretic effect, anti-cholesterol, and anti-diabetic effects of Hibiscus sabdariffa have been demonstrated in several studies. Constituents of different plant parts of Hibiscus sabdariffa include phenolic acids, organic acid, flavonoids and anthocyanins which may contribute to the pharmacological effects of the plant. Hibiscus sabdariffa is relatively safe as LD50 of its extract in rats was found to be above 5000 mg/kg. Therefore, Hibiscus sabdariffa because of its pharmacological and nutritional benefits could be exploited in the management of various pathological conditions such as cardiovascular disease, cancer, neurological disorders and diabetes.

Keywords: Anthocyanins, Antihypertensive, Hepato-protective, Hibiscus sabdariffa Phenolic acids
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How to cite this article:

Owoade, A. O., Adetutu, A., Olorunnisola, O. S., 2019. A review of chemical constituents and pharmacological properties of Hibiscus sabdariffa L.Int.J.Curr.Res.Biosci.Plantbiol. 6(4): 42-51 . doi: https://doi.org/10.20546/ijcrbp.2019.604.006