|Online ISSN : 2349-8080
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2 College of Public and Medicine, Wolaita Sodo University, Ethiopia
Maerua oblongifolia was among other medicinal plants those were extensively used medicinal plants for treatment of human and domestic animals in addition to serving as detergent for washing purpose.The present study was developed to contribute to the documentation of the pharmacological and biological activity testing through extraction, isolation, and characterization of crude extracts of leaves of most popularly used traditional medicinal plant, Maerua oblongifolia. Air dried leaf powder of Maerua oblongifolia was exhaustively extracted with methanol at room temperature. Fractionation of the column elution started with 30 ml of pure diethyl ether, followed by increasing polarity of solvent system, diethyl ether, ethylacetate, ethanol, methanol, water, 32 fractions were collected. This study has resulted in the isolation and characterization of MOM-19.Characterization was done by spectroscopic technique, Nuclear Magnetic Resonance (NMR).The 13C NMR spectrum of the compound showed well resolved resonance of 38 carbon atoms. The number of carbon atom indicated that it was a triterpene. The result of this study was important as the search for new pharmacologically active compounds from plant extracts that may led to the discovery of many clinically useful drugs.