Online ISSN : 2349-8080 Issues : 12 per year Publisher : Excellent Publishers Email : editorinchiefijcrbp@gmail.com |
The article contains data on the technology of obtaining and biological activity of the freeze-dried and cryopreserved forms of the turkey herpes virus culture used for the manufacture of the vaccine against Marek's disease. Using the methods of stationary and roller cultivation, a culture biomass of the herpes virus of turkeys was obtained, which was subjected to sublimation and cryopreservation in a mixture of two different stabilizing components. The titration results of these two forms of the vaccine showed that the virus titer was maintained at a level sufficient to be used as a vaccine for the immunization of chickens against Marek's disease.