Abstract                 Volume:4  Issue-8  Year-2017          Original Research Articles

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Effects of Aqueous Extract of Sterculia setigera Delile (Sterculiaceae) on Exercise-Induced Bronchospasm
Judith F. Ahounou Aïkpe1,2, B. Huguette Akakpo1,2, André Hamadou1, Serge F. Sossou1,Joachim D. Gbénou2* and Pierre H. Dansou1
1 Laboratory of Effort Physiology, National Institute of Youth, Physical and Sport Education, University of Abomey-Calavi,01 BP 169, Porto-Novo, Republic of Benin
2 Laboratory of Pharmacognosy and Essential Oils, Faculty of Sciences and Techniques   University of Abomey-Calavi,01 BP 918, ISBA, Cotonou, Republic of Benin
*Corresponding author
Abstract:

Sterculia setigera Delile (Sterculiaceae) is a plant commonly used in African traditional medicine and pharmacopoeia to treat many pathology including cough and asthma. The present study aim to evaluate the effect of aqueous extract of Sterculia setigera leaves on exercise-induced bronchospasm in athletes. Subjects underwent a treadmill bronchial test and a spirometry test before and after treatment with this aqueous extract. The comparison of subjects ventilatory parameters is carried out and certain inflammatory proteins tested. The results showed that aqueous extract of Sterculia setigera leaves improved significantly the ventilation parameters of subjects and declined the percentage in forced expiratory volume per second (FEV1). Subjects Blood concentration in C-reactive protein (CPR) and erythrocyte sedimentation rate were also be reduced. These results justify the traditional use of Sterculia setigera in the treatment of asthma and cough in Benin. This extract can therefore be used in the treatment of asthma or exercise-induced bronchospasm (EIB) in elite athletes.

Keywords: C-reactive protein,Exercise-induced bronchospasm,Sterculia setigera
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How to cite this article:

Ahounou Aïkpe, J. F., Huguette Akakpo, B., Hamadou, A., Sossou, S. F., Gbénou, J. D., Dansou, P. H., 2017. Effects of aqueous extract of Sterculia setigera Delile (Sterculiaceae) on exercise-induced bronchospasm.Int.J.Curr.Res.Biosci.Plantbiol. 4(8): 8-14. doi: https://doi.org/10.20546/ijcrbp.2017.408.002