'' '' '' '' '' ''

Abstract                 Volume:3  Issue-10  Year-2016          Original Research Articles

IJCRBP is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCRBP Articles.

Online ISSN : 2349-8080
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorinchiefijcrbp@gmail.com

Anti-inflammatory Activity of Traditionally Important Insulin Plant Costus Species for the Treatment of Inflammation in Human
M. Ferosekhan1, A. Ramu1* and S. Ravikumar2
1Department of Chemistry, Madurai Kamaraj University, Madurai - 625 021, Tamil Nadu, India
2Department of Oceanography and Coastal Area Studies, Alagappa University, Thondi Campus, Thondi – 623 409,Tamil Nadu, India
*Corresponding author

Fresh elder leaves of species viz., Costus pictus and Costus speciosus were collected from Western Ghats, Tamil Nadu. Leaves were washed thrice in sterile distilled water and shade dried and powdered. Then 500g of powdered leaves was soaked in 1 litre of ethanol water mixture (3:1) for 10 days in an air tight clean glass container. Mixing was done every day so as to enable to enhance the maximum extraction of bioactive compounds.  After that, the solvent containing bioactive extracts were filtered through muslin cloth and kept in the rotary flash evaporator (with solvent trap) so as to obtain solvent free extract residue and tested for in vitro assessment of anti-inflammatory property. Leaf extract of C. pictus and C. speciosus at different concentrations provided significant protection against denaturation of proteins. The C. pictus extract showed maximum percentage inhibition of 97.87% at 400 mg/ml, whereas C. speciosus gave 86.04% at 400 mg/ml. Diclofenac sodium, a standard anti-inflammatory drug showed the maximum inhibition 97.56% at the concentration of 400 mg/ml. So it can be concluded from the present study that, the C. pictus and C. speciosus leaf extract can be used as an anti-inflammatory agent.

Keywords: Anti-inflammatory,Bio-active compounds,Costus species,Insulin plants,Phytochemicals,Traditional medicinal plants
Download this article as Download

How to cite this article:

Ferosekhan, M., Ramu, A., Ravikumar, S., 2016. Anti-inflammatory activity of traditionally important insulin plant Costus species for the treatment of inflammation in human.Int.J.Curr.Res.Biosci.Plantbiol. 3(10): 144-149. doi: http://dx.doi.org/10.20546/ijcrbp.2016.310.017
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.